《英文msh詞典》GABA B Receptor
[入口詞] GABA B Receptor
[主題詞] Receptors,GABA-B
[英文釋義] Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and influence cells via interactions with G-proteins. GABA-B receptors are pharmacologically characterized by their insensitivity to the blocker bicuculline and sensitivity to the agonist L-baclofen. They are found both presynaptically and postsynaptically,and act variously by inhibition of adenylate cyclase,activation of phospholipase A2,activation of potassium channels,and inactivation of voltage-activated calcium channels.